Research

Real-world trial evaluating visual outcomes as well as visual aberrations post-implantation of the trifocal PanOptix IOL at the time of cataract surgery

• PI: Alanna Nattis, DO
• Sub-I’s: Richard Nattis MD, John Passarelli MD, Jordan Garelick MD, Craig Richter MD, Jeffrey Martin MD
• Sponsor: Alcon
• Presented at the American Society of Cataract and Refractive Surgery meeting 

Real-world trial evaluating dry eye symptom improvement with adjunctive loteprednol eye drops to routine lifitegrast use BID

• PI: Alanna Nattis, DO
• Sub-I’s: Richard Nattis MD
• Sponsor: Bausch & Lomb

Evaluation of post-corneal crosslinking pain and inflammation utilizing a dexamethasone intracanalicular insert vs. topical prednisolone

• PI: Alanna Nattis, DO
• Sponsor: Ocular Therapeutix
• Presented at the American Society of Cataract and Refractive Surgery meeting
• Published in the Journal of Cataract and Refractive Surgery

Imaging study evaluating change in corneal stromal thickness using anterior segment OCT while on topical human recombinant nerve growth factor eye drops

• PI: Brad Kligman MD
• Sponsor: Dompe

Real-world trial evaluating visual outcomes as well as visual aberrations post-implantation of the extended depth of focus Vivity IOL at the time of cataract surgery

• PI: Alanna Nattis, DO
• Sub-I’s: Richard Nattis MD, John Passarelli MD, Jordan Garelick MD, Craig Richter MD, Eric Rosenberg DO
• Sponsor: Alcon
• Presented at the American Society of Cataract and Refractive Surgery meeting

Evaluation of visual outcomes and dry eye signs/symptoms post-femtosecond laser cataract surgery with use of intracanalicular dexamethasone insert at the time of surgery

Evaluation in a long-term follow up time frame of the AcrySof single-piece and AcrySof multi-piece monofocal intraocular lenses

• PI: John Passarelli MD
• Sponsor: Ocular Therapeutix

Evaluation of visual outcomes and signs of cystoid macular edema in patients undergoing cataract surgery using the NGENUITY 3D Cataract Surgery system vs. conventional operative microscope

Long-term evaluation of patients post-bilateral implantation of Clareon Panoptix and/or Vivity intraocular lenses

• PI: Eric Rosenberg DO
• Sponsor: Alcon
• Presented at the American Society of Cataract and Refractive Surgery meeting
• Published in The Journal of Cataract and Refractive Surgery

Comparison and validation of standard intraocular pressure, (IOP) keratometry and pachymetry measurements vs. a novel 4-in-1 device that measures IOP, keratometry and pachymetry in a non-contact method in one sitting.

• PI: Alanna Nattis, DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Topcon

Evaluation of treatment of dry eye with recombinant human nerve growth factor (Oxervate) vs. Vehicle

• PI: Alanna Nattis, DO
• Sub-I: Richard Nattis MD
• Sponsor: Dompe

Evaluation of novel device that is implanted in the trabecular meshwork and releases travoprost continuously to lower intraocular pressure in glaucoma patients. Device lasts 3 years

*PIVOTAL Trial – SightMD’s partnership here helped provide positive data that allowed this device to be FDA approved – first of its kind; has revolutionized the way we can treat glaucoma

• PI: Alanna Nattis, DO
• Sub-I’s: Richard Nattis MD, Raju Sarwal MD
• Sponsor: Glaukos

Retrospective identification of patients having undergone monofocal and toric intraocular lens implantation for a novel software to help make cataract surgery planning more efficient

• PI: Alanna Nattis, DO
• Sub-I: Richard Nattis MD
• Sponsor: Alcon

Evaluation of novel varenicline nasal spray in subjections with early stage neurotrophic keratopathy

• PI: Alanna Nattis, DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Oyster Point Pharmaceuticals

Evaluation of safety and efficacy of novel cold-receptor modulator eye drop to help treat dry eye

*PIVOTAL Trial: Drop is now FDA approved

• PI: Brad Kligman MD
• Sponsor: Aerie Pharmaceuticals

Evaluation of safety and efficacy of phentolamine eye drops for treatment of presbyopia

• PI: Jeffrey Martin MD
• Sponsor: Ocuphire

Evaluation of visual outcomes in patients with Alcon monofocal and monofocal toric intraocular lenses

• PI: Alanna Nattis, DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Alcon

Evaluation of visual outcomes in patients with bilaterally implanted Alcon Clareon Panoptix and Vivity intraocular lenses

• PI: Alanna Nattis, DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Alcon

Evaluation of symptomatic improvement and use of adjunctive medical treatment for patients with diagnosis of demodex blepharitis – from both the provider and patient side (survey-based study in addition to documentation of clinical findings)

• PI: Alanna Nattis, DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Tarsus

Novel study evaluating effect of systemic C5 inhibition on geographic atrophy (GA) lesion growth over 1 year as well as measures of functional disease progression

*PIVOTAL Trial: Unique Phase 3 trial utilizing a novel treatment method for GA, rather than observation and intravitreal injections. Has potential to change the way GA and macular degeneration is treated as a whole.

• PI: Edward Marcus, MD
• Sponsor: Regeneron

Evaluation of symptomatic improvement of visual disturbances and improvement in visual acuity in patients who had previously undergone keratorefractive surgery (LASIK, PRK)

• PI: Jeffrey Martin MD
• Sponsor: Oculos

Evaluation of treatment patterns and safety of Izervay in routine clinical practice (“real world study”) for the treatment of geographic atrophy (GA) secondary to age related macular degeneration (AMD)

• PI: Edward Marcus MD
• Sponsor: Astellas Pharma

Evaluation of outcomes for patients with confirmed bacterial conjunctivitis following treatment with BID Fucithalmic (novel antibiotic to the US, widespread use with excellent broad spectrum activity noted outside of the US).

• PI: Alanna Nattis DO
• Sub-I: Eric Rosenberg DO
• Sponsor: Baxis Pharmaceuticals

Evaluation of outcomes for patients in a real-world setting after surgery with the C-REX ™ Goniotomy instrument in patients with primary open angle glaucoma, as characterized by change in intraocular pressure, use of ocular hypotensive medications, ocular adverse events

• PI: Raju Sarwal MD
• Sponsor: Iantrek

Retrospective evaluation of patient outcomes following treatment with the STREAMLINE surgical system for glaucoma

• PI: Raju Sarwal MD
• Sponsor: New World Medical